Dr. Macrene's Cosmetic Classification of Skin Aging*
Fine Line & Wrinkles AppearanceΒ β fine and coarse lines on face and neck.
Laxity AppearanceΒ β sagging skin, such as folds around the mouth and marionette lines, jowels, and loss of firmnessΒ to the neck.
UnevenΒ ComplexionΒ β loss of lusterΒ in the undereye area, upper lip, and cheeks.
Uneven Skin ToneΒ β appearance of ageΒ blotches and blemishes.
Loss of RadianceΒ β ruddy appearance on the nose, chin, and eventually the rest of the face.
Textural ChangesΒ β appearance of roughness and unevenness which worsens over time.
Decrease inΒ LuminosityΒ β dullness to skin which worsens over time.
* Alexiades-Armenakas M.R., Dover J.S., Arndt K.A. The spectrum of laser resurfacing: non-ablative, fractional and ablative laser resurfacing. J Amer Acad Dermatol 2008 May; 58(5): 719-740
37 Actives provides the most potent proven ingredients to address each category of cosmetic skin aging actively combined in a single cream. Β Independent testing by an esteemed laboratory confirmed clinical results for each category by objective quantitative measurements of the appearance of wrinkles, appearance of blotches and skin tone.