High Performance Face Cream Extra Rich

One-Step Skincare Solution

The same frontier-level actives as the High Performance Face Cream — in a richer, more deeply nourishing base built for dry skin, mature skin, compromised barriers, and the demands of winter or dry climates year-round.

This is an enriched version of the core formula — it is the same clinically rigorous active architecture, the same copper lysinate/prolinate, the same Plankton, Micrococcus, Arabidopsis DNA repair system, the same MA37® patented complex of 37 active classes — delivered in a more emollient, barrier-intensive base designed for skin that needs more. Drier skin types. More mature skin. Skin compromised by climate, over-exfoliation, or a weakened barrier. And anyone whose skin has reached the stage of life where a standard cream is no longer enough.

Where the High Performance Face Cream is the architectural foundation, the Extra Rich is the same foundation reinforced — deeper nourishment, stronger barrier repair, and the sustained hydration that dry and mature skin demands year-round.

What Makes It Richer

The Extra Rich replaces the lighter squalane-forward base of the original cream with a more emollient system built on hydrogenated olive oil unsaponifiables, cocoa seed butter, hydrogenated coco-glycerides, and jojoba esters — a quartet of plant-derived lipids that are structurally closer to the skin's own barrier composition than conventional emollients, delivering richness that absorbs rather than sits.

The result is a noticeably more nourishing texture that melts into skin without heaviness, providing the sustained occlusion that compromised and dry skin barriers need to stop transepidermal water loss and begin genuinely rebuilding.

Key Actives

MA37® patented complex — Dr. Alexiades's patented system of 37 classes of actives, the scientific foundation of every DR. MACRENE actives formula. Deployed here in full, addressing firmness, hydration, barrier integrity, environmental defense, cellular repair, and luminosity simultaneously — in a base engineered to deliver them deeper into dry, barrier-compromised skin.

Copper lysinate/prolinate — a rarely used, technically demanding copper peptide — Copper chelated to lysine and proline, the amino acid building blocks of collagen, for exceptional bioavailability and stability. Directly stimulates collagen and elastin synthesis at the fibroblast level, accelerates skin repair, and visibly firms and restructures over time. One of the most clinically validated actives in dermatology — and one of the least used in skincare due to its formulation complexity and cost. Present here because dry and mature skin needs collagen support most.

Plankton, Micrococcus, Arabidopsis DNA repair system — the ingredients almost no one works with — Marine and terrestrial plant enzyme extracts with a scientifically documented ability to repair UV-induced DNA damage in skin cells. Costly, pH-sensitive, reactive with common preservative systems, and technically demanding to stabilize. Very few formulators attempt it. The cumulative DNA damage it addresses is amplified in dry, mature, and barrier-compromised skin — making its inclusion here not just scientifically justified but clinically essential.

Ergothioneine — A longevity molecule with a dedicated cellular transporter in human skin, protecting mitochondrial DNA from oxidative damage. Rarely seen in skincare due to cost and sourcing complexity. Particularly valuable for mature skin where cellular antioxidant defenses are diminished.

Cocoa seed butter & jojoba esters — Deep nourishing emollients that reinforce the lipid barrier and restore the skin's natural ability to retain moisture, providing the sustained occlusion that dry and compromised skin cannot generate on its own.

Hydrogenated olive oil unsaponifiables — The biologically active fraction of olive oil, rich in squalene precursors and phytosterols that mimic the skin's own lipid structure. Deeply regenerative for barrier-depleted skin, restoring elasticity and suppleness with a richness that does not feel heavy.

Silver ear mushroom extract (Tremella fuciformis) — A botanical hyaluronic acid alternative with superior water-holding capacity, delivering deep sustained hydration while supporting the skin's own moisture regulation — particularly important in dry climates and winter conditions where atmospheric humidity is low.

Hydrolyzed hyaluronic acid — Small-molecule HA for maximum penetration, drawing moisture into the deeper skin layers where dry and mature skin needs it most.

Antioxidant complex — Edelweiss, microalgae, plankton, green coffee, yerba mate, feverfew, red algae, resveratrol, and stabilized vitamin C form a comprehensive defense against the environmental oxidative stress that is amplified in winter conditions and compromised skin.

Full amino acid complex — Mirrors the skin's own natural moisturizing factors to continuously restore barrier integrity, softness, and the appearance of smooth, healthy skin — replenishing what dry and mature skin is no longer producing efficiently on its own.

Caffeine & bisabolol — Targeted depuffing and botanical anti-inflammatory support to calm the redness and chronic low-grade inflammation that compromised barrier skin is particularly prone to.

Who It Is For

This cream is for you if your skin feels tight after cleansing, drinks in moisturizer without feeling satisfied, reacts to cold air or dry environments, or has simply reached the stage of life where a standard cream is no longer enough. It is also the right choice for anyone whose barrier has been compromised by over-exfoliation, retinoids, or aggressive treatments.

Use it as your winter cream, your dry-climate travel companion, or your year-round solution if your skin has always leaned dry.

How It Works With Your Routine

Serum → intensive correction, lifting, and active delivery

Extra Rich Cream → deep barrier reinforcement, structural rebuilding, and sustained moisture lock

The serum opens the pathway. The Extra Rich Cream seals, nourishes, and rebuilds at the level dry and mature skin actually requires.

The Science Behind the Formula

The same ingredients that make the High Performance Face Cream exceptional — the copper lysinate/prolinate, the Micrococcus lysate, the ergothioneine — are present here in a base that was specifically engineered to deliver them to skin that has lost its ability to hold onto moisture and maintain its own barrier. Dr. Alexiades did not simply add more emollient to the original formula. She rebuilt the base around the biology of dry and compromised skin — then loaded it with the same frontier-level actives that make the original cream unlike anything else on the market.

The difficulty of sourcing and stabilizing these ingredients does not change between formulas. What changes is who needs them most. And dry, mature, barrier-compromised skin needs them most.

What You Will See

Immediately: Deeply nourished, visibly smoother skin with an immediate sense of relief, restored suppleness, and a rich but non-greasy feel.

With regular use: Measurably firmer skin, softened fine lines and wrinkles, significantly reduced dryness and tightness, strengthened barrier function, reduced redness, and a sustained healthy glow that reflects skin that is genuinely more resilient — through winter and beyond.