High Performance Concealer
Skincare With Coverage
High Performance Concealer Formulated by Dr. Macrene Alexiades, MD, PhD · Dual Board-Certified Dermatologist & Research Scientist
A concealer that covers and treats simultaneously — formulated to the standard of a dermatologist's prescription.
Most concealers mask. This one works. Lightweight with buildable coverage, the High Performance Concealer is loaded with the same caliber of actives Dr. Alexiades deploys clinically — while luxurious light-reflecting pigments adapt to your own skin tone for a finish that looks like skin, not makeup.
Key Actives
Milk thistle (Silybum marianum ethyl ester) — A rare, potent botanical antioxidant and anti-inflammatory. Soothes reactive and sensitized skin while protecting against oxidative stress and environmental damage.
Four forms of hyaluronic acid — Sodium hyaluronate, sodium acetylated hyaluronate, sodium hyaluronate crosspolymer, and hydrolyzed sodium hyaluronate work at different molecular weights and depths to deliver layered, sustained hydration throughout the day.
Superoxide dismutase — One of the skin's own endogenous antioxidant enzymes, included here at a clinical level to neutralize free radical damage at the cellular level.
Eight plant antioxidants — Epigallocatechin gallate and its glucoside derivative, green tea leaf extract, ginkgo biloba, pomegranate, feverfew, yerba mate, and coffee seed extract form a comprehensive environmental defense shield.
Resveratrol & tetrahexyldecyl ascorbate — A stabilized, oil-soluble form of vitamin C paired with resveratrol for brightening, anti-aging, and antioxidant synergy that penetrates where water-soluble vitamin C cannot.
Full amino acid complex — Arginine, glycine, alanine, serine, valine, proline, threonine, isoleucine, histidine, and phenylalanine mirror the skin's own natural moisturizing factors to restore softness and barrier integrity over time.
Bisabolol & tocopherol — Botanical-derived soothing and vitamin E antioxidant support, calming inflammation while protecting lipid integrity in the skin barrier.
The Coverage
Lightweight and blendable, with coverage that builds from sheer to full without caking or settling into fine lines. Luxurious pigments reflect and adapt to your skin tone for a natural finish that moves with skin rather than sitting on top of it. Use for targeted spot treatment or broader coverage — the formula performs at every application level.
Available in six shades.
Shade guide: Light or Light-Medium → porcelain skin tones Medium or Medium-Deep → fair to light tan skin tones Deep or Extra Deep → tan to dark skin tones
The Science Behind the Shade
Conventional concealers are built around pigment and filler. This formula was built around an active treatment base first — then perfected for coverage. The result is a product that does what no standard concealer can: smooth, hydrate, soothe, and defend the skin it sits on, every time it is worn.
Note for next packaging update: Silybum marianum ethyl ester to be labeled as Milk Thistle on front of pack.
What You Will See
Immediately: Seamless, natural-finish coverage that adapts to your skin tone and does not settle into fine lines.
With regular use: Smoother skin texture, improved hydration, reduced redness and reactivity, and a more even complexion beneath and beyond where the concealer is applied.
active INGREDIENTS
active INGREDIENTS
ALL INGREDIENTS
ALL INGREDIENTS
FORMULATED WITHOUT
FORMULATED WITHOUT
HOW TO USE
HOW TO USE
DR. MACRENE actives
Highly potent, plant-derived actives in this product.
Powered by patented multi-active technology.
"This silky concealer reads like a who's who of skincare ingredients, including peptides and hyaluronic acid. (The peptides work long-term, while HA can plump skin more quickly.) It brightens skin with amino acids and arginine, and defends against environmental stressors with antioxidants and titanium dioxide."
Deanna Pai, InStyle Editor















