CLEAN DERMATOLOGIC SCIENCE | Featured Products
High Performance Face Serum
Soothe, hydrate, firm, and even skin tone with this highly active, lightweight serum that will help to reduce the appearance of fine lines and wrinkles. Proven to lift and tighten crepiness while reducing blotches and evening skin tone, this serum repairs skin barrier while assisting in DNA restoration. Use after Macrene Actives High Performance Face Cream to seal in actives and achieve best results.
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Our Mission
Farm-to-Face: Medicinal botanicals sourced from Dr. Macrene's organic farm are extracted in her plant science laboratory followed by clinical trials on real patients in her Park Avenue dermatology research clinic and practice. Backed by plant science & dermatology research in her clinic, organic farm and lab, Dr. Macrene’s revolutionary formulas rejuvenate the skin with clean, active ingredients for visible restoration to take the place of cosmetic procedures. Organic, clean, scientifically proven and clinically tested plant derivatives are hand-made in small batches to deliver dermatologic grade efficacy, diminish signs of aging, and protect the skin from environmental pollutants and toxins. Experience real results that replenish, restore and rejuvenate skin to replace cosmetic procedures.
About Macrene Actives
Our Story
Dr. Macrene Alexiades, M.D, Ph.D. Derm-Scientist
With three degrees in Medicine and Genetics from Harvard University and Double Boarded in Dermatology in the US and EU, Dr. Macrene is the most sought after dermatologist for high-profile clients for over two decades. With a Fulbright in agricultural science & her own organic farm and lab, this industry leader has achieved unparalleled results translating cosmetic procedures into skincare with her award-winning formulas of breakthrough plant and sea-sourced skincare solutions.
Replace Cosmetic Procedures With Active Ingredients
“Dermatologist Dr. Macrene Alexiades launched MACRENE actives with the goal to ultimately replace cosmetic
procedures with skincare that achieves the same results.” -FORBES
“...eliminated skincare layering by creating a one-and-done cream with all the ingredients you’ll ever need.”
“...literally wrote the book on modern-day dermatology.”
