CLEAN DERMATOLOGIC SCIENCE | Featured Products
One-Step Skincare Solution
Ideal for dry and mature skin, this ultra-rich face cream is packed withVitamins C & E, red algae, andcoconut-based glyceridesto deliver a lush dose of hydration that’s ideal for night time or post-procedure needs. Proven to intensely hydrate while helping to reduce the appearance of fine lines, blemishes and redness, this extra rich cream smooths skin texture while repairing skin barrier and balance.
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Our Mission
Farm-to-Face: Medicinal botanicals sourced from Dr. Macrene's organic farm are extracted in her plant science laboratory followed by clinical trials on real patients in her Park Avenue dermatology research clinic and practice. Backed by plant science & dermatology research in her clinic, organic farm and lab, Dr. Macrene’s revolutionary formulas rejuvenate the skin with clean, active ingredients for visible restoration to take the place of cosmetic procedures. Organic, clean, scientifically-proven and clinically-tested plant derivatives are hand-made in small batches to deliver results, diminish signs of aging, and protect the skin from environmental pollutants and toxins. Experience real results that replenish, restore and rejuvenate skin to replace procedures.
About Macrene Actives
Our Story
Dr. Macrene Alexiades, M.D, Ph.D. Derm-Scientist
With three degrees in Medicine and Genetics from Harvard University and Double Boarded in Dermatology in the US and EU, Dr. Macrene is the most sought after dermatologist for high-profile clients for over two decades. With a Fulbright in agricultural science, her own organic farm and lab, this industry leader has achieved unparalleled results translating cosmetic procedures into skincare with her award-winning formulas of breakthrough plant and sea-sourced skincare solutions.
"This modern approach to facial rejuvenation has replaced nip-and-tuck-surgeries"
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Award-Winning Formula
The High Performance Extra Rich Cream is packed with organic plant-based active ingredients like vitamins C & E, red algae, and coconut-based glycerides to deliver a lush dose of hydration that’s ideal for night time or post-procedure needs.
“Dermatologist Dr. Macrene Alexiades launched MACRENE actives with the goal to ultimately replace cosmetic
procedures with skincare that achieves the same results.”
“...eliminated skincare layering by creating a one-and-done cream with all the ingredients you’ll ever need.”
“...literally wrote the book on modern-day dermatology.”
