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Naturally Plush

20 organic plant-derived actives in a clean, vegan, paraben-free, phthalate-free, sulfate-free, glycol-free, silicone-free, fragrance-free formula.  Clean oil and hyaluronic acid spheres fill the lips without injections. Peptides plump and ceramides heal chapped lips with a host of antioxidants and oils to nurture.

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Our Mission

Backed by plant science from her organic farm and lab, Dr. Macrene’s revolutionary formulas nourish the skin with clean, active ingredients for visible restoration. Organic, clinically-tested plant derivatives are hand-made in small batches in her lab to deliver results, diminish signs of aging, and protect the skin from environmental pollutants and toxins.

About Macrene Actives

Sustainably Sourced

Macrene Actives High Performance Face Cream

"This modern approach to facial rejuvenation has replaced nip-and-tuck-surgeries"


“...recognized, respected, and recommended in New York City and beyond.”

“...eliminated skincare layering by creating a one-and-done cream with all the ingredients you’ll ever need.”

“...literally wrote the book on modern-day dermatology.”



The Texture and tone of my skin improved dramatically. I can go out of the house without makeup now and still get compliments.


Skin feels and looks so much better!


I have used this product for about 4 years I have very sensitive skin n I am unable to use most products but this cream has done wonders for my face I am not kidding I will use nothing else.


I have one word Amazing! Very happy with my choice.

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