Our Mission
Farm-to-Face: Medicinal botanicals sourced from Dr. Macrene's organic farms in Upstate New York and Greece are extracted in her plant science laboratory followed by clinical trials on real patients in her Park Avenue dermatology research clinic & practice. Backed by plant science & clinical dermatology research, Dr. Macrene’s revolutionary formulas help rejuvenate the skin with clean actives for visible restoration aimed to replace cosmetic procedures. Organic, clean, scientifically proven & clinically tested plant derivatives are hand-made in small batches to deliver dermatologic grade efficacy, help diminish signs of aging, & help protect the skin from the environment. Experience real results that replenish, restore & rejuvenate to replace cosmetic procedures.
About Macrene Actives
Our Story
Dr. Macrene Alexiades, M.D, Ph.D. Derm-Scientist
With three degrees in Medicine and Genetics from Harvard University and Double Boarded in Dermatology in the US and EU, Dr. Macrene is the most sought after dermatologist for high-profile clients for over two decades. With a Fulbright in agricultural science & her own organic farm and lab, this industry leader has achieved unparalleled results translating cosmetic procedures into skincare with her award-winning formulas of breakthrough plant and sea-sourced skincare solutions.
"The first luxury skincare to deliver the medicinal properties of Greece cultivated over thousands of years."
—Dr. Macrene
Shop Now“Dermatologist Dr. Macrene Alexiades launched MACRENE actives with the goal to ultimately replace cosmetic
procedures with skincare that achieves the same results.” -FORBES
“...eliminated skincare layering by creating a one-and-done cream with all the ingredients you’ll ever need.”
“...literally wrote the book on modern-day dermatology.”
