Summer Hydration Bundle
Bundle our best selling High Performance Cleanser + High Performance Serum for $260 ($290 value)
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New MACRENE actives Loyalty Program
Skyros Grecian Body Collection
The first luxury Grecian medicinal botanical line in the world
Skin + Earth
Support The Mission to Eliminate Plastics for Earth Month and All Year Long
The Skyros Collection
The Essential Collection
Skyros Grecian Medicinal Botanical Skincare
Discover the Powerful Plant Actives of the Greek IslandsShop Now
Dr. Macrene Alexiades, M.D, Ph.D. Derm-Scientist
With three degrees in Medicine and Genetics from Harvard University and Double Boarded in Dermatology in the US and EU, Dr. Macrene is not only the most sought after dermatologist for high-profile clients for over two decades, but her research on clean sustainable plant based solutions dates back over 40 years. With a Fulbright in agricultural science & her own organic farm and lab, this industry leader has achieved unparalleled results translating cosmetic procedures into skincare with her award-winning formulas of breakthrough plant and sea-sourced skincare solutions packaged in glass, wood and paperboard for the health of your skin and the earth.
"The first luxury skincare to deliver the medicinal properties of Greece cultivated over thousands of years."
—Dr. MacreneShop Now
“Dermatologist Dr. Macrene Alexiades launched MACRENE actives with the goal to ultimately replace cosmetic procedures with skincare that achieves the same results.” -FORBES
"Dr. Macrene may be Michaelangelo with a needle, but her eye cream replaces procedures. "
“...eliminated skincare layering by creating a one-and-done cream with all the ingredients you’ll ever need.”
“...literally wrote the book on modern-day dermatology.”
The Texture and tone of my skin improved dramatically. I can go out of the house without makeup now and still get compliments.
Skin feels and looks so much better!
I have used this product for about 4 years I have very sensitive skin n I am unable to use most products but this cream has done wonders for my face I am not kidding I will use nothing else.
THE ONE THAT I WAITED FOR
I have one word Amazing! Very happy with my choice.