The Skyros Collection
The Essential Collection
Skyros Grecian Medicinal Botanical Skincare
Discover the Powerful Plant Actives of the Greek Islands
Shop NowDr. Macrene Alexiades, M.D, Ph.D. Derm-Scientist
With three degrees in Medicine and Genetics from Harvard University and Double Boarded in Dermatology in the US and EU, Dr. Macrene is not only the most sought after dermatologist for high-profile clients for over two decades, but her research on clean sustainable plant based solutions dates back over 40 years. With a Fulbright in agricultural science & her own organic farm and lab, this industry leader has achieved unparalleled results translating cosmetic procedures into skincare with her award-winning formulas of breakthrough plant and sea-sourced skincare solutions packaged in glass, wood and paperboard for the health of your skin and the earth.
"The first luxury skincare to deliver the medicinal properties of Greece cultivated over thousands of years."
—Dr. Macrene
Shop Now“Dermatologist Dr. Macrene Alexiades launched MACRENE actives with the goal to ultimately replace cosmetic procedures with skincare that achieves the same results.” -FORBES
"Dr. Macrene may be Michaelangelo with a needle, but her eye cream replaces procedures. "
“...eliminated skincare layering by creating a one-and-done cream with all the ingredients you’ll ever need.”
“...literally wrote the book on modern-day dermatology.”