Luxury Anti-Aging Skincare by Dermatologist Dr. Macrene

RESTORE YOUR SKIN FOR FALL

15% Off Any Face Cream with Serum Purchase*

Unlock a special offer on this potent pair.

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NEW

High Performance Eye Mask

Complete skincare around the eyes.

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DR. MACRENE actives

Clean Dermatological
Science, Replacing Cosmetic
Procedures

ABOUT DR. MACRENE

Dr. Macrene Alexiades, MD, PhD, Dermatologist-Scientist

Trust your skin to the world's only Dermatologist-Scientist, MD, PhD, Founder, and Formulator.

With three degrees from Harvard in Medicine and Genetics and Double Board-Certified in Dermatology in the US and EU, Dr. Macrene is not only the world's #1 dermatologist for high-profile clients for over two decades, but her research on clean sustainable plant based solutions dates back over 40 years.

Dermatological, Science-Backed Skincare

CLINICALLY PROVEN RESULTS

High Performance
Lip Filler

Science

96%

Agree it gives their lips a radiant glow

100%

Agree their lips look silkier after application

100%

Agree their lips feel more moisturized

93%

Agree their lips feel soft, smooth, and more hydrated

*In an 8-week clinical test of 27 subjects, ages 37-68

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In the Press

On her Skyros property, she has begun harvesting medicinal herbs that grow wild on the island—anti-inflammatory lemon verbena, antibacterial lemon balm, and skin-tightening linden — for the latest addition to Macrene actives.

Emma Elwick-Bates, Vogue

This eponymous line from New York City dermatologist Macrene Alexiades, MD, PhD, is known for doubling down on active ingredients, some of which are harvested from her own organic farm in Dutchess County, New York.

Dianna Mazzone Singh, allure

The High Performance Lip Filler is one I can't recommend enough, as it's a standout favorite from the product line. The formula provides a subtle plumping effect without the intense stinging that can often accompany a volume-boosting lip treatment.

Deanna Pai, Vanity Fair

MACRENE actives delivers a minimalist, yet impactful approach to skincare, emphasizing the importance of a consistent routine with products like their High Performance Face Cream for skin restoration.

Porter