The Discovery Set

Name: The Discovery Set
Brand: MACRENE actives
SKU: 1004
Price: 295.0 USD
Availability: InStock

$295.00

~~$370.00~~ $295.00

Product variants

pH Balancing

Firming

Smoothening

Depuffing

Give the Gift of Derm-Science Skincare

Discovery Set Formulated by Dr. Macrene Alexiades, MD, PhD · Dual Board-Certified Dermatologist & Research Scientist

Five clinically-formulated essentials. One complete introduction to the science of better skin.

The Discovery Set brings together Dr. Alexiades's most foundational treatments — from lips to eyes — in one curated collection. Each product is built on the same 20+ active philosophy that defines the DR. MACRENE actives line: no filler ingredients, no compromises, every formula carrying a full clinical payload.

A $370 value at $295 ($75 courtesy), presented in an organic hemp and cotton zip pouch.

What's Inside

High Performance Cleanser — 2 oz. An antioxidant-rich cleanse that removes impurities without stripping the skin's natural barrier. The clinical starting point for every DR. MACRENE actives routine.

High Performance Face Serum — 0.5 oz. A lifting, brightening concentrate formulated to visibly firm and luminize. Delivers active ingredients at the concentration and depth a dermatologist would specify.

High Performance Lip Filler — Clear, 0.2 oz. The injection-free lip treatment. Peptides, micro-encapsulated hyaluronic acids, ceramides, and 20 therapeutic antioxidants work with every wear to plump, smooth, and protect.

High Performance Eye Masks — 2 single masks Dr. Alexiades's newest innovation for the most delicate and revealing area of the face. Powered by peptides, hyaluronic acid, antioxidants, and brighteners to visibly refresh, depuff, and restore a more youthful contour — results you will see immediately.

Organic Hemp & Cotton Zip Pouch A reusable, sustainably sourced travel pouch. Curated to keep your routine together, at home or away.

What You Will See

Immediately: Brighter, more refreshed skin and visibly smoother, more hydrated lips and eye area.

With regular use: Visibly firmer skin, improved luminosity, reduced fine lines, and sustained lip and eye area plumpness — without injection.

The DR. MACRENE actives Difference

Every product in this set was formulated by a physician who spent decades in clinical practice before creating a single formula. Where most skincare brands work with cosmetic chemists to approximate results, Dr. Alexiades built each product around the active ingredients she prescribed — then engineered them to penetrate, perform, and last. This is where science meets nature, and where a beginner's introduction to skincare becomes a genuinely clinical one.

Includes High Performance Cleanser 2 oz. · High Performance Face Serum 0.5 oz. · High Performance Lip Filler Clear 0.2 oz. · High Performance Eye Mask Single x2 · Organic Hemp & Cotton Zip Pouch

A $370 value at $295 ($75 courtesy).

active INGREDIENTS

High Performance Cleanser

Plant-Derived Surfactants: Coconut Oil-Derived, Plant Glucosides and Amino Acid Surfactants
Non-Comedogenic: Niacinamide (Vitamin B3), Biotin (Vitamin B7), Citric Acid, Spearmint & Peppermint Extracts
Anti-Oxidants: Green Tea, Pomegranate, Olive Leaf Extracts
Skin Barrier Actives: Panthenol (Vitamin B5), Saccharide Isomerate
Moisturizing Emollients: Glycerin, Aloe, Olive Leaf, Biotin

High Performance Face Serum

Anti-Wrinkle: Hyaluronic Acids, Peptides, Vitamin C, Proline
Lifting Agents: Palmitoyl hydroxyproline peptides high concentration
Anti-Oxidants: Green Tea Extract, Pomegranate Extract, Vitamins C and E

Chria High Performance Lip Filler

Lip Filler: Microencapsulated Hyaluronic Acid
Anti-Wrinkle: Dipalmitoyl hydroxyproline Peptide
Anti-Chap: Coconut Oil, Ceramides, Shea Butter, Squalane, Plant Octyl Lipids
Anti-Oxidants: Vitamin E, Rosemary Extract, and Echium plantagineum
Emollient / Moisturizers: Camelia Seed Oil, Sunflower Oil, Echium Plantagineum Oil, Palm Oil, Shea Butter
Natural Fresheners: Peppermint Oil, Spearmint Oil
Plumpers: Goldenrod Extract, Sesamum Seed Extract, Cnidium monnieri Fruit Extract

High Performance Eye Mask

Depuffers: Green Tea Leaf, Organic Plant Caffeine, Lactobacillus Ferment
Brighteners: Amino Acid Complex
Wrinkle Reducers: Peptides, Micro-Encapsulated Hyaluronic Acid [Sodium Hyaluronate]
Skin Calmers: Aloe Vera Leaf Juice, Mimosa Bark
Antioxidants: Pomegranate Flower

ALL INGREDIENTS

High Performance Cleanser

Water (Aqua), Sodium Cocoyl Isethionate¹, Potassium Cocoyl Glycinate¹, Stearic Acid¹, Glycerin¹, Coco-Caprylate/Caprate, Sorbitan Stearate, Potassium Cocoate¹, Sodium Hydroxypropyl Starch Phosphate¹, Camellia Sinensis (Green Tea) Leaf Extract¹²³, Punica Granatum (Pomegranate) Juice Extract¹²³, Aloe Barbadensis Leaf Extract¹², Olea Europaea (Olive) Leaf Extract¹², Mentha Viridis (Spearmint) Leaf Extract¹², Mentha Piperita (Peppermint) Leaf Extract¹², Saccharide Isomerate³, Niacinamide, Panthenol, Biotin, Sodium Phytate¹, Caprylhydroxamic Acid¹, Decyl Glucoside, Lauryl Glucoside, Citric Acid¹³, Sodium Citrate¹³, Glyceryl Caprylate¹, Mentha Viridis (Spearmint) Extract¹², Mentha Piperita (Peppermint) Extract¹², Alcohol¹.

¹Plant-Derived • ²USDA-Certified Organic • ³Third Party-Certified

High Performance Face Serum

Water (Aqua), Hydrogenated Ethylhexyl Olivate¹³, Glycerin¹, Squalane¹²³, Cetyl Alcohol¹, Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables¹, Sorbitan Stearate, Dipalmitoyl Hydroxyproline¹³, Hydrogenated Olive Oil Unsaponifiables¹, Jojoba Esters¹³, Hydrolyzed Hyaluronic Acid, Camellia Sinensis (Green Tea) Leaf Extract¹²³, Punica Granatum (Pomegranate) Extract¹²³, Chrysanthemum Parthenium (Feverfew) Extract¹²³, Ilex Paraguariensis (Yerba Mate Tea) Leaf Extract¹²³, Coffea Robusta (Green Coffee) Seed Extract¹²³, Theobroma Cacao (Cocoa) Seed Butter¹²³, Tremella Fuciformis Sporocarp (Silver Ear Mushroom) Extract¹³, Citrullus Lanatus (Watermelon) Fruit Extract¹, Kappaphycus Alvarezii Extract¹, Scenedesmus Rubescens (Microalgae) Extract¹, Resveratrol¹, Bisabolol¹, Tocopherol¹, Tetrahexyldecyl Ascorbate, Disodium Acetyl Glucosamine Phosphate, Citrulline¹, Sodium Lactate, Arginine¹, Aspartic Acid¹, Palmitic Acid, PCA¹, Glycine, Alanine, Serine, Valine¹, Proline¹, Threonine¹, Isoleucine¹, Histidine¹, Phenylalanine¹, Sodium PCA¹, Hydrogenated Lecithin¹³, Hydroxypropylmethylcellulose Stearoxyether, Sodium Phytate¹, Sodium Benzoate, Sodium Methyl Stearoyl Taurate, Potassium Sorbate, Ethylhexylglycerin¹, Alcohol¹, Oryza Sativa (Rice) Bran Extract¹, Rosmarinus Officinalis (Rosemary) Leaf Extract¹, Helianthus Annuus (Sunflower) Seed Extract¹, Phenoxyethanol, Leontopodium Alpinum (Edelweiss) Flower/Leaf Extract¹³, Helianthus Annuus (Sunflower) Seed Oil, Sodium Stearoyl Glutamate, Xanthan Gum, Caffeine, Sodium Hydroxide, Citric Acid¹³.

¹Plant-Derived • ²USDA-Certified Organic • ³Third
Party-Certified

Chria High Performance Tinted Lip Filler

Hydrogenated Polyisobutene, Cocos Nucifera (Coconut) Oil1, Squalane1,3, Camellia Japonica Seed Oil1, Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables1, Caprylic/Capric Triglyceride1, Ethylhexyl Palmitate1, Butyrospermum Parkii (Shea) Butter1,2, Echium Plantagineum Seed Oil1, Dipalmitoyl Hydroxyproline1,3, Dimethyl Isosorbide, Octyldodecanol1,3, Octyldodecyl Oleate1,3, Mentha Arvensis Leaf Oil1, Butyrospermum Parkii (Shea) Butter Unsaponifiables1,2, Octyldodecyl Stearoyl Stearate1,3, Helianthus Annuus (Sunflower) Seed Oil1, Sesamum Indicum (Sesame) Seed Extract1, Tocopherol1, Ceramide NG1, Glycine Soja (Soybean) Oil1, Silica Dimethyl Silylate, Cnidium Monnieri Fruit Extract1,3, Rosmarinus Officinalis (Rosemary) Leaf Extract1,3, Butylene Glycol, Pentylene Glycol, Alcohol1,3, Solidago Virgaurea (Goldenrod) Extract1,3, Sodium Hyaluronate.

High Performance Eye Mask

Water (Aqua/Eau), Glycerin 1,3 , Aloe Barbadensis (Aloe Vera) Leaf Juice 1 , Propanediol 1 , Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Camellia Sinensis (Green Tea) Leaf Extract 1,3 , Punica Granatum (Pomegranate) Flower Extract 1,3 , Albizia Julibrissin (Mimosa) Bark Extract 1,3 , Dipotassium Glycyrrhizate 1 , Darutoside 1,3 , Panthenol Allantoin, Lactobacillus Ferment Lysate 3 , Lactobacillus Ferment 3 , Tetrasodium Glutamate Diacetate 1,3 , Serine, Valine 1 , Isoleucine 1 , Proline 1 , Threonine 1 , Sodium Citrate 1 , Histidine 1 , Phenylalanine 1 , Sodium Lactate, Caffeine 1,3 , Arginine 1 , Aspartic Acid 1 , Glycine, Alanine, Citric Acid 1,2 , PCA 1 , Sodium PCA 1 , Caprylhydroxamic Acid 1 , Potassium Sorbate, Xanthan Gum, Phenoxyethanol, Sodium Benzoate

1 Plant-Derived – 2 Organic – 3 Third Party Certified

FORMULATED WITHOUT

Gluten
Parabens
Phthalates
Sulfates
Fragrance
Acrylate
Propylene-Glycol
Mineral Oil
Petrolatum
Animal Byproducts
Mica
Talc
Silicone

HOW TO USE

High Performance Cleanser

Use the DR. MACRENE actives High Performance Cleanser in the morning and evening to gently cleanse the skin of face, neck and décolletage.

Apply one to two pumps to clean, moist hands and lather into a foam. Spread over the face in gentle, circular motions before taking it off with lukewarm water.

Carefully dab at the skin with a clean towel until it is damp, before applying the High Performance Face Cream (sold separately) or any other DR. MACRENE actives product.

High Performance Face Serum

Use the DR. MACRENE actives High Performance Face Serum after the Face Cream (sold separately) or as stand-alone product.

Apply pea-sized amount on slightly damp skin and spread in gentle motions. Focus on areas that experience sagging such as eye, forehead, and the jawline.

Wait until the Serum has been completely absorbed by the skin before applying any other product of your choice.

Chria High Performance Tinted Lip Filler

Shake the DR. MACRENE actives Chria High Performance Lip Filler well and use applicator wand to carefully mix the product. Apply a dab of Lip Filler to the lower and upper lip at least two times a day and as often as desired.

The Clear Lip Filler can also be used above the lips to visibly reduce wrinkles and other signs of aging.

High Performance Eye Mask

Cleanse face with the High Performance Cleanser and pat dry. Open the packet, pull out tray. Carefully remove mask, peel off protective cotton layers, and apply biocellulose gel mask to undereye and crow's feet area. Leave on for 10–20 minutes. Use 2–3 times per week, or prior to special events as part of your skin prep. For optimal results, use in combination with the High Performance Eye Cream (sold separately).