Dr. Macrene Alexiades

Dr. Macrene: The Derm-Scientist

Macrene Alexiades, MD PhD FAAD holds three degrees from Harvard University: a BA from Harvard University, MD from Harvard Medical School, and a PhD in Genetics from Harvard University. She was a Fulbright Scholar with a research award in Europe. 

At Harvard, she was elected to Phi Beta Kappa and awarded the Fay Prize, the highest undergraduate honor; at Harvard Medical School, she was honored in the Dean’s Report and received the Paul Dudley White Award. At Harvard Graduate School of Arts and Science, she was awarded grants from the National Institutes of Health, National Eye Institute and Radcliffe College. As dermatology resident at New York University School of Medicine, she served as Chief Resident and awarded the Husik Prize for her dermatologic research. She has been honored in Who's Who, the People's Choice Awards, Cosmetic Executive Women, and voted #1 Dermatologist in the USA by Aesthetic Everything. She has been named as a Castle Connolly Top Doctor since 2014. Dr Macrene received Who's Who Lifetime Achievement Award, Industry Leaders and American Women Award, Exceptional Women in Medicine, and New York Magazine's Top Doctors. 

She is a Fellow of the American Academy of Dermatology and American Society for Laser Medicine and Surgery. She has achieved the rare status of Double Board-Certification in Dermatology in the European Union as well as the US, she is certified to practice medicine, surgery and dermatology in the EU. 

She is the Assistant Editor of the journal Dermatologic Surgery. She is Senior Associate Editor for the Journal of Drugs in Dermatology, Editor for Lasers in Surgery and Medicine, and Reviewer for the JAMA Dermatology, Journal of the American Academy of Dermatology, Dermatologic Surgery, Journal of Lasers in Medicine and Surgery, Journal of Cosmetic Surgery, Cosmetic Dermatology, Journal of Cosmetic and Laser Therapy, Journal of Photobiology and Photomedicine and the Journal of the European Academy of Dermatology and Venereology, among others. She serves on the board of ASLMS, the Pan-American Photodynamic Therapy Association, Vice President of the Board of the Promenade Condominium, Board of the William Woodward School, the Archdiocesan Cathedral of the Holy Trinity,  Aesthetic Buyers Guide, Candela Lasers, and Cutera Lasers.  She has served as Chair of Research for the American Society for Dermatologic Surgery, author of her own Laser and Cosmetic News column for the Journal of Drugs in Dermatology, and biographed in Who’s Who.  She is the ASLMS representative to the Laser Institute of America.

Dr. Alexiades' textbook entitled, COSMETIC DERMATOLOGIC SURGERY, by Wolters-Kluwer-Lippincott is published, and her latest textbook, PHOTODYNAMIC THERAPY by Elsevier is scheduled to publish this year.

She has served as Dermatologist and Skin Care Expert for L’Oreal, Paris with whom she developed an acne skin care line before she created her own skincare research company, MACRENE actives. In April 2014 Lancome USA announced her as their leading Consulting Dermatologist & skincare authority, for whom she collaborated on skincare innovation & research projects. Her own skincare line MACRENE actives has launched in Sephora.

She is a Diplomate of both the American and European Boards of Dermatology and Assistant Clinical Professor at Yale University School of Medicine.  She founded and directs her dermatology, laser surgery and research center in Manhattan and a lab-based skin care research company NY Derm LLC.  She is an attending at Lenox Hill Hospital, Yale/New Haven Hospital and Yale/West Haven VA Hospital.  

Dr. Alexiades has numerous publications and discoveries in the fields of basic science, dermatology and laser surgery.  Her practice and academic work are focused on topical dermatologic anti-cancer and anti-aging therapies, laser technology and skin rejuvenation.

For more information or to schedule an interview with Dr. Macrene, please contact us:

phone 212-570-2067 or 917-293-4610 or contact@macreneactives.com

For Dr. Alexiades's Dermatology Practice email@nyderm.org


Harvard Medical School, Boston, MA
Doctor of Medicine, June 1997

Harvard University, Cambridge, MA
Doctorate of Philosophy in Genetics, June 1997

Harvard University, Cambridge, MA
Bachelor of Arts Degree in Biology, June 1989

Current Titles

Associate Clinical Professor, Yale University School of Medicine, 2003-present

Director, Dermatology and Laser Surgery Private Practice, 955 Park Avenue, New York, NY August 2003- present

President and CEO, NY Derm LLC, Dr. Macrene Skin Results, 37 Extreme Actives

Attending Physician, Lenox Hill Hospital, Yale New Haven and Yale West Haven VA Hospitals

Fellow, American Academy of Dermatology

Fellow, American Society for Laser Medicine and Surgery

Adjunct Clinical Professor, University of Athens, Sygros Hospital

Past Titles

Consulting Dermatologist Skin Care Expert Worldwide
   L’Oreal, Paris May 2005-2008

Director of Research, Laser & Skin Surgery Center of New York
   New York, New York 10016 August 2001-2003

Post-Graduate Education

Internship, Internal Medicine, Lenox Hill Hospital, NY 1997-8

Residency, Dermatology, NYU School of Medicine1998-2000

Chief Residency Dermatology, NYU School of Medicine 2000-2001

Board Certification

Diplomate, American Board of Dermatology, October 2002

Credentialed, Medicine and Surgery, EU, July 2004

Dermatology Boards, EU, June 2009

Licensure in Medicine and Surgery

New York State, July 1997-present

Connecticut State, November 2004-present

European Union, July 2004-present

Board and Committee Memberships

Allergan, Medical Advisory Board

ASLMS Representative, Laser Institute of America

Pan-American Photodynamic Therapy Association

Promenade Condominium Board of Managers, Vice President 2008-Present

William Woodward School Board of Directors, 2002-Present

Archdiocese of North America Cathedral of Holy Trinity Board of Trustees 2009-11

Harvard Committee, Office of Admissions: 2002-present

The Dermatology and Aesthetic Surgery International League, Organizing Committee 2009-present

Primaeva Medical, Medical Advisory Board, 2008-2010

Cutera, Medical Advisory Board, 2008-present

Aesthetic Buyers Guide, Editorial Advisory Board, 2007-present

Syneron Lasers, Medical Advisory Board, 2005-2007

The Cathedral School, Chair of Afternoon School PA 2007-2009

The Chapin School, Science Advisor, 2006-present, Art Committee 2004-2005, Parents Association 2004-2005, Founder, Chapin Tennis Club, Class I 2005-2006.

American Society for Dermatologic Surgery, Chairman of Research 2004-2007; Committee 2002-2007; Council on Education and Research Activities: 2004-2007; Work Group 2010- Present

Harvard Medical School M.D./Ph.D. Program Steering Committee: 1993 - 1994

Harvard Medical School M.D./Ph.D. Retreat Committee: 1992 - 1994

Harvard Medical School Minority Recruitment Committee: 1992 - 1995

Harvard Medical School Advanced Biomedical Sciences Committee:  1993 – 1995

  • Chancellor of New York Roll of Honor for Community Service 1985                                                   
  • Elizabeth Agassiz Scholar                                                          1985 -1989
  • John Harvard Scholar                                                                 1985 - 1989
  • Frank Tarr Scholar                                                                       1985 - 1989
  • Capt. Jonathon Fay Prize (Highest Harvard/Radcliffe Honor)    1989
  • Phi Beta Kappa (Iota chapter)                                                     1989
  • Harvard Medical School Dean’s Report                                      1996
  • Fulbright Scholar                                                                          1989-1990
  • Who’s Who of American Women                                                  2005-present
  • Who’s Who in America                                                                  2006-present
  • Who’s Who in the World                                                                2007-present
  • Leading Health Professional of the World                                     2009-present
  • Who’s Who Among Medical Professionals                                    2009-present
  • Cambridge Who’s Who                                                                  2009-present
  • People’s Choice Awards: Best Doctor                                           2010, 2011
  • Project ALS Brainy Women                                                            2011
  • Most Compassionate Doctor Award                                              2012
  • #1 Dermatologist in USA, Aesthetic Everything                             2013
  • Castle Connolly Top Doctor                                                           2014-present
  • Who's Who Lifetime Achievement Award                                     2017
  • Who's Who Industry Leaders Award                                             2017
  • Who's Who American Women Award                                           2017
  • Who's Who of America                                                                 2017
  • New York Magazine Top Doctors                                                  2017
  • Westinghouse Science Talent Search Award                      1983-1984
  • Governor’s Committee on Scholastic Achievement of New York Scholarship                      1984 - 1989
  • Victor Posner Award                                                                         1984 - 1989
  • Radcliffe Science Research Fellowship                                            1986
  • Harvard Bureau of Study Counsel Tutor Supervisor Award         1986 - 1989
  • Fulbright Scholar                                                                              1989 - 1990
  • Paul Dudley White Research Fellowship                                         1991
  • National Eye Institute Training Grant                                              1992 - 1995
  • Medical Scientist Training Program Scholarship (NIH)                   1990 – 1997
  • Husik Prize (New York University Dermatology Research Prize)    2001
  • Journal of Drugs in Dermatology Research Competition First Place  2004
  • Top Ten Presentation American Society for Lasers in Medicine and Surgery 2007
  • Top Five Treatments in New York, The New York Post 2008
  • Patient Choice Awards: Best Doctor Award 2010, 2011
  • Most Compassionate Doctor Award 2012
  • Cosmetic Executive Women: Beauty Quest Award 2014
Academic Appointments / Hospital Affiliations

Assistant Clinical Professor, Yale University School of Medicine, October 2003 - present

Attending Physician, Yale New Haven Hospital, 2003-present

Attending Physician, Yale West Haven VA Hospital, 2006-present

Attending Physician, Lenox Hill Hospital, 2001-present


Massachusetts Medical Society: 1992 - 1997

Harvard Hellenic Association and Hellenic Society: 1992 - 1997

Hellenic Medical Society: 1996 - present

American Academy of Dermatology: 1997-present

American Society of Laser Medicine and Surgery: Fellow 2001-present

American Society for Dermatologic Surgery: 2001-present

Dermatology Foundation: 1999-

Women’s Dermatologic Society: 2006-present

DASIL, founding member, 2010-present

Journal and Extracurricular Activities

The Harvard Crimson, Editorial Board and Art Editor, 1985 - 1989

The Harvard Political Review, Art Editor, 1985 - 1989

The Biology Review, Staff Writer and Art Editor, Harvard University, 1986 – 1989

Harvard University Bureau of Study Council, Tutor Supervisor, 1985-1989

Harvard University Rape Crisis Counselor (Response center/hotline), 1988 -1989

Harvard Greek Club, 1986 - 1990

Harvard Medical School, Room 166 Peer Counselor, 1990 - 1992

Harvard Medical School, Vanderbilt Hall Athletic Facility, Yoga Instructor, 1990 - 1992

William Woodward Nursery School: President, Parents Association; Chair,  Fundraising Committee; Board Member: 2003-present

Metropolitan Opera House, Patron: 2003-present

Dermatologic Surgery journal, Editorial Board, 2009-present; Staff Reviewer: 2001-present

Journal of Drugs in Dermatology, Senior Associate Editor, Editorial Board, and Columnist of “Laser and Cosmetic News”: 2005-present

Lasers in Surgery and Medicine, Reviewer, 2007-present

Journal of Cosmetic and Laser Therapy, Reviewer, 2008-present

Promenade Condominium, Vice President of Board of Managers, 2008-present

Journal of Cosmetic Dermatology, Reviewer, 2008-present

European Journal of European Academy of Dermatology and Venereology, Reviewer, 2009-present

The Promenade Newsletter, Editor-in-Chief, 2009-present.

Archives of Dermatology, Reviewer, 2009-present

Journal of Photobiology and Photomedicine, Reviewer 2009-present

American Society for Laser Medicine and Surgery, Strategic Planning Committee, 2013

Residents for Reasonable Development, Founder, New York City 2013


Laboratory Researcher, Department of Cellular and Developmental Biology, Harvard University: 1984 to 1991

Photoregulation of plant gene expression
Director: Lawrence Bogorad, Ph.D

Insect development
Director: Carroll Williams, Ph.D

Fulbright Scholar, Institute of Molecular Biology and Biotechnology, Heraklion, Crete: 1989 to 1990

Isolation and genetic engineering of ice-strains of Pseudomonas in Greece for agricultural crop protection against frost injury
Director: Fotis Kafatos, Ph.D.

Paul Dudley White Research Fellow, Department of Hygiene and Epidemiology, University of Athens Medical School: 1991

Evaluation of the effect of emergency measures on air pollution levels in the city of Athens
Director: Dimitrios Trichopoulos, M.D., Ph.D.

Doctorate Researcher, Department of Genetics, Harvard Medical School: 1991 to 1997

Cell fate determination in the vertebrate retina
Director: Constance Cepko, Ph.D.

Director of Research, Laser and Skin Surgery Center of New York, 2001-2003.

Chair of Research Committee, American Society for Dermatologic Surgery 2004-present

Director of Research, Dermatology and Laser Surgery, Private Practice and in affiliation with Yale University School of Medicine, 2003-present

Principle Investigator, NY Derm LLC, dermatologic therapy laboratory, 2008-present


Please see the PUBLICATIONS page.

Patent Application

Geronemus, R., Alexiades-Armenakas, M.R., and McMillan, K. High fluence rate activation of photosensitizers for dermatologic applications. United States Patent Application number 20040073277, Serial number 407921, April 15, 2004.


Portraiture, Sculpture, Drawing, Painting, Skiing, Yoga (teacher trained), Tennis, Photography


Fluent in Modern Greek; Proficient in Spanish