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Working to Make Cosmetic Procedures Obsolete

Dr. Macrene Alexiades


Macrene Alexiades, MD PhD FAAD holds three degrees from Harvard University: a BA from Harvard University, MD from Harvard Medical School, and a PhD in Genetics from Harvard University, and she was a Fulbright Scholar with a research award year in Europe. Dr. Macrene is a Fellow of the American Academy of Dermatology and American Society for Laser Medicine and Surgery, and has achieved the rare status of Double Board-Certification in Dermatology in the European Union as well as the US.

Dr. Macrene is a Diplomat of both the American and European Boards of Dermatology and Assistant Clinical Professor at Yale University School of Medicine.  She founded and directs her dermatology, laser surgery and research center in Manhattan and a lab-based skin care research company NY Derm LLC.  She is an attending at Lenox Hill Hospital, Yale/New Haven Hospital and Yale/West Haven VA Hospital.  

Dr. Macrene has numerous publications and discoveries in the fields of basic science, dermatology and laser surgery.  Her practice and academic work are focused on topical dermatologic anti-cancer and anti-aging therapies, laser technology and skin rejuvenation.

Dr. Macrene's Qualifications

The Cream That Started It All


Originally launched in 2009 as 37 Actives, Dr. Macrene Alexiades's High Performance Anti-Aging Face Cream was the first to use Hyaluronic Acid as an ingredient, long before the trend. Continuing to be at the forefront of skincare and with the mission to make clinical procedures obsolete, Macrene Actives remains the cleanest, effective, anti-wrinkle, non-acnegenic products on the market. 

Straight from the Source

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Frequently asked questions about Macrene Active's most popular products.

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