InStyle:The Best Dark Spot Correctors for Uneven Skin Tone—After Testing Over Two Dozen

Dr. Macrene Alexiades was recently featured in InStyle's comprehensive guide to dark spots, where she shared her clinical perspective on prevention, protective ingredients, and the importance of understanding your skin type before choosing corrective treatments. 

On blue light damage:

“We probably are accumulating some light damage just from looking at screens,” says Dr. Alexiades. “If we’re in front of any light source for long enough, sooner or later, those wavelengths will get into the skin, to the DNA, and can cause trouble.”

On dark spots:

Dr. Alexiades says that some of us simply have a genetic predisposition to developing dark spots. “A lot of brown spots are associated with systemic disease, and that is inherited,” she explains.

Over three decades of dermatological research and practice have shaped Dr. Macrene's approach to hyperpigmentation—one centered on prevention rather than correction. That philosophy extends beyond the clinic into how she advises patients on ingredient selection and daily protection.

Shop dark spot correcting skincare by Dr. Macrene here, and read the full article below.