
From summer sun damage to seasonal dehydration, discover Dr. Macrene's dermatologist-recommended approach to transitioning your skin for fall.
As summer gives way to cooler air and lower humidity, skin needs a different kind of care. Dr. Macrene Alexiades, MD, PhD, recently joined KTLA to walk viewers through the seasonal shift — addressing the sun exposure, dehydration, and barrier disruption that summer leaves behind, and outlining a dermatologist's approach to healthy-looking skin this fall.
Her Recommendations
1. Address Sunspots & Uneven Tone
Months of sun exposure can leave visible marks on the skin — uneven pigmentation, dullness, loss of radiance. Dr. Macrene points to antioxidants and brightening ingredients, particularly vitamin C, to help visibly improve tone and restore luminosity.
2. Replenish the Skin Barrier
Between sun exposure and the drop in humidity, the skin barrier takes a hit heading into fall. Richer, lipid-rich formulas — built with fatty acids and ceramides — help replenish moisture and support barrier function as the seasons change.
3. Target Signs of Photoaging
Fine lines, wrinkles, uneven texture, and loss of elasticity are often the lasting signature of summer sun. Peptides and retinoids can help address these visible signs of photoaging, supporting a firmer, smoother-looking complexion.

Discover the Full Segment
Dr. Macrene's fall skin guide offers a clear, dermatologist-backed framework for the seasonal transition — grounded in the same clinical authority and prevention-first philosophy behind DR. MACRENE actives. Watch the full segment for her recommended ingredients, treatments, and seasonal adjustments.